For this reason, knowing the factors that lead to the outcomes of patients under IMV in the ICU is vital to inform the professionals’ conduct better and advise their families ( 6). However, around 38% of the patients that require IMV still die ( 5). ![]() IMV is a complex resource, and the team’s expertise in managing it might generate better results. In such a context, critical patients admitted to an ICU might require the use of invasive mechanical ventilation (IMV) to maintain patent airways, improve oxygenation, and prevent aspiration ( 3, 4). It is, therefore, a specialized facility to monitor and stabilize the patients’ clinical aspects ( 2). The intensive care unit (ICU) provides advanced life support to critical patients presenting different severity levels ( 1). The PEEP >8 cmH 2O at admission was also associated with increased mortality since this value is a marker of initially severe hypoxia. Regarding risk predictors, several demographic and clinical characteristics were associated with enhanced mortality in intensive care unit patients under mechanical ventilation, such as diabetes mellitus, systemic arterial hypertension, and older age. The binary logistic regression was significant in predicting the patients’ risk of death [ X 2 (9) = 288.335 p 8 cmH 2O at admission (OR = 2.153 95%CI = 1.426–3.250).Ĭonclusion: The death rate of the studied intensive care unit was equivalent to that of other similar units. Results: We analyzed 1,443 medical records out of those, 570 (39.5%) recorded the patients’ deaths. We associated the patients’ features with the risk of death using a multivariate binary logistic regression analysis. We considered the following characteristics in the statistical analysis: demographic data, diagnostic hypothesis, hospitalization data, and PEEP and PaO 2 during IMV. Methods: We conducted an epidemiological study analyzing medical records of inpatients who received IMV from January 2016 to December 2019 prior to the Coronavirus Disease (COVID)-19 pandemic in Brazil. Also, to evaluate the risks associated with death and the influence of positive end-expiratory pressure (PEEP) and arterial oxygen pressure (PaO 2) at admission in the clinical outcome. ![]() Therefore, our objective was to describe the epidemiological profile of adult patients in intensive care that required IMV in-hospital treatment. Introduction: Understanding the epidemiological profile and risk factors associated with invasive mechanical ventilation (IMV) is essential to manage the patients better and to improve health services. 2Laboratory of Human and Medical Genetics, Bragança Paulista, São Francisco University, São Paulo, Brazil.1Laboratory of Cell and Molecular Tumor Biology and Bioactive Compounds, São Francisco University, Bragança Paulista, São Paulo, Brazil.Camila Vantini Capasso Palamim 1,2 † Matheus Negri Boschiero 1,2 † Fernando Augusto Lima Marson 1,2 * †
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